The prevalence of glaucoma that has been reported specifically in populations with diabetes ranges from 2.5% to 15.6% 7. The incidence of glaucoma is increased by 36% in patients with diabetes compared to patients without diabetes 8.
Both Diabetes and Glaucoma share common risk factors; diabetes and hyperglycaemia (too high blood glucose) are associated with glycation of lipids(altering of lipids (fat) in a negative way due to diabetes) and abnormalities of lipid metabolism which may increase oxidative stress and promote cellular apoptosis (cell death) – the same mechanism by which Retinal Ganglion Cell loss occurs in glaucoma1. Additionally, the presence of diabetes and elevated fasting glucose levels are associated with elevated levels of intraocular pressure.
Non- modifiable risk factors for glaucoma include:
The only modifiable risk factor is intraocular pressure and as such presents as the mainstay of current glaucoma treatment 1.
Diabetics with Non Proliferative Diabetes-related Retinopathy are more likely to develop primary open angle glaucoma, whereas people with diabetes with Proliferative Diabetes-related Retinopathy are more likely to develop angle-closure glaucoma 9.